Detection of changes in allelic frequencies due to selection on complex traits in the genomes of pigs from four genetic lines using generation proxy selection mapping
Most economically relevant traits in pig breeding programs are controlled by numerous causal variants spread across the genome and undergo selection pressure to improve the genetic merit of commercial pigs. As a result, small changes in allele frequency over relatively…
CANCER PRIORITY BY RACE
Cancer is one of the most common and deadly diseases and its incidence is increasing. There are over one hundred types of cancer and they have a varied impact on society and the individuals affected. Racial disparities play a role…
De-novo SuperTranscriptome assembly from the nodal root growth zone of maize inbred line FR697
Certain cultivars of maize show increased resistance to water deficit conditions by maintenance of root growth. To better understand the molecular mechanisms related to this adaption, nodal root growth zone samples were collected from the reference inbred line B73 and…
Design and Evaluation of a Longitudinal Method to Measure Physician Burnout in the Clinical Workflow
Burnout, a condition characterized by emotional exhaustion, listlessness, and an inability to cope, is demonstrably more prevalent among healthcare providers than other occupations. Burnout is fundamentally a longitudinal problem, but traditional instruments for measurement such as the Maslach Burnout Inventory…
Analysis and Dissemination of School-based Immunization Data to Improve Public Health Outcomes in Missouri
In Missouri, immunization is required for both public and private school students against common vaccine-preventable diseases (VPDs) including polio, pertussis, varicella, measles, mumps, and rubella; however, parents may forego vaccination for their child by claiming medical or religious exemptions. Like…
Computational Subgroups Stratification and Precision Drug Repositioning Using Explainable Artificial Intelligence
Enabling precision medicine requires developing robust patient stratification methods and identifying drugs tailored to homogeneous subgroups of patients from a heterogeneous population. Once discovering these subgroups, we can align patients and medications more specifically to achieve precision-based therapy. Developing de novo drugs…
Virtual Campus Visit with NSF CISE AD Dr. Margaret Martonosi
The National Science Foundation (NSF) supports a majority of US academic research in the Computer and Information Science and Engineering (CISE) topic areas. Since February, 2020, Dr. Margaret Martonosi serves as NSF CISE AD, stewarding the CISE directorate’s $1B annual budget on behalf…
Dissertation Defense – Utilizing Blockchain Technology for Clinical Trial Optimization
Clinical trials are the cornerstone of treatment discovery because they provide comprehensive scientific evidence on the safety, efficacy, and optimal use of therapeutics. However, current clinical trials are facing multiple challenges such as patient recruitment, data capture, and overall management.
Comprehensive Exam Announcement – A Case-Control based Genomic Analysis of Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a respiratory illness that affects millions of people all over the world. It is a major cause of chronic morbidity and mortality and a serious global public health problem. COPD is the fourth leading…