Automated Large-Scale File Preparation and Docking: Evaluation of ITScore and STScore Using the 2012 Community Structure−Activity Resource Benchmark

We present the first study utilizing the full set of compounds from the recently released 2012 Community Structure−Activity Resource (CSAR) data set. The CSAR data set is a realistic benchmark for protein-ligand docking scoring functions, containing 57 crystal structures and…

Simulation based Training for Medical Skills: Comparative Effectiveness of Training Methods and Evaluating the Translational Impact

Simulation based medical education is gaining wide spread appeal as a means to increase medical skill training opportunities and enhance patient safety in a changing medical environment. Two factors have accelerated the adoption of patient simulation in health care including;…

Large-Scale Pairwise Alignments on GPU Clusters: Exploring the Implementation Space

Several problems in computational biology require the all-against-all pairwise comparisons of tens of thousands of individual biological sequences. Each such comparison can be performed with the well-known Needleman-Wunsch alignment algorithm. However, with the rapid growth of biological databases, performing all…

TeleMDID: Mobile Technology Applications for Interactive Diagnoses in Teledermatology

A web-based dermatology image management application, Missouri Dermatology Image Database (MDID), has been developed to facilitate dermatology practices. The digital images captured offsite are transferred to MDID’s secure server via encrypted connection and user authentication. Uploaded images can be organized…

A Study of User Behaviors in Web-based Medical Image Management and Search

Medical professionals in various specialties work closely with digital images for diagnosis, research and education. Electronic applications of image management are emerging in virtually every medical specialty, including cardiology, radiology, pathology, dermatology, orthopedics, OB/GYN etc.  Compared to radiology, there is…

Decision Tree Induction for the Screening of Patients at Risk of Moderately Emetogenic Chemotherapy-Induced Nausea and Vomiting During Delayed Phase

Chemotherapy-Induced Nausea and Vomiting (CINV) are the most feared and common side-effects of chemotherapy for cancer patients. The main care plan for CINV consists of preventative care using antiemetics before chemotherapy. CINV considerably impairs the life quality of cancer patients…

The MDID project: A study of dermatological image archive, search and use behaviors

A novel, web-based dermatology image management application (MDID) has been developed to facilitate the practices in the Department of Dermatology at the University of Missouri School of Medicine. Since its launch in early January, there are over 1700 images of…