Tool Development for Analyzing Arrhythmias in Fast Cardiac Magnetic Resonance Scans
Cardiac magnetic resonance (CMR) scanning provides a method to diagnose cardiac disease. For obtaining an effective image, the standard procedure of CMR requires patients to hold their breath during the scanning, but it is difficult for frail patients in clinic.
Using Big Data to Identify Possible External Risk Factors for Poorly Understood Cancers
Worldwide, cancer is the second leading cause of death (Cancer, 2012). There were 17 million new cases and 9.6 million cancer deaths worldwide in 2018, including approximately 1.7 million new U.S. cases and 600,000 U.S. cancer deaths (Cancer Facts & Figures 2018 |…
An Evaluation of Physician Burnout by EMR Use Characterization and Correlation
Burnout disproportionately affects healthcare workers and continues to rise. This condition potentially contributes to cost, quality and patient safety risk in an already overburdened United States healthcare system. While the causes of burnout are complex, evidence exists pointing to Electronic Medical Record…
Early Detection of Glaucoma Using Electronic Health Records
Glaucoma is the second leading cause of irreversible blindness worldwide. About 70 million people have glaucoma, and nearly 4.4 million people are blind from optic nerve damage due to undiagnosed glaucoma. Besides, the current glaucoma growth rate and its economic…
Evaluation of chronic disease self-management information on social media using evidenced-based frameworks
The management of chronic diseases requires considerable patient education and self-management. Diabetes, cancer and mental illness are among the top ten searched chronic diseases on social media, a platform where people increasingly seek and disseminate information. Social media platforms such…
Elucidate the Genome Evolution of Eusocial Corbiculate Bees Using Parent-progeny Sequencing Approach
Understanding the evolution of eusociality, defined by distinct reproductive and nonreproductive castes, at the molecular level, has always been an essential and highly challenging topic of biology. Eusociality has evolved multiple times independently and involved many incremental steps, resulted in…
Analysis of snRNA-seq from CDX Models of Non-Small Cell Lung Cancer Identified Subpopulation of Cells Potentially Responsible for Tumor Progression
Circulating tumor cells (CTCs) are considered as seeds of metastasis and have potential to be used as biomarkers in cancer. Understanding the biology of CTCs is critical to evaluate tumor progression and response to treatment. Additionally, studying transcriptome of CTCs–derived tumors…
What to Learn and What to Avoid from ClinicalTrials.gov for New Trial Design When Repurposing Drugs for Precision Medicine?
Clinical trials are essential in the process of new drug development and repositioning. As clinical trials involve significant investments of time and money, it is crucial for trial designers to carefully investigate trial settings prior to launching it. In the…
A Case-Control based Genomic Analysis of Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a respiratory illness that affects millions of people all over the world. It is a major cause of chronic morbidity and mortality and a serious global public health problem. COPD is the fourth leading…