Biological pathways as graphs: comparison of select similarity methods
We extracted biomedical pathways from 47 publications related to non-small cell lung cancer (NSCLC) and mergedthem into a Neo4j graph database. With this graph serving as ground truth for comparing to other pathways that were extracted from other publications, we investigated several methods of calculating graph similarity. Unlike ontologies and engineered data sets that…
MUIDSI Comprehensive Exam — Measuring Geodiversity in Remotely-Sensed Imagery: Deep Spatial Change Detection Methods for Dataset Bias Mitigation and Visual Landscape Characterization
Amid explosive growth in availability of multimodal remotely sensed imagery (RSI) data from a constellation of overhead sensors, a lack of understanding persists concerning the actual content of these data sources, in particular the nature of spatial variation in the…
GIScience as an Interdisciplinary Bridge in Indigenous Health Equity
GIS and geographic theories can help bridge a crucial gap in interdisciplinary research projects. Geography is uniquely poised to offer critical and practical analytical support, wrangle spatial data and relate them to other datasets, and ground community-based science within the…
Impact of diabetes status and other factors on risk for thrombotic and thromboembolic events: A multicenter, retrospective analysis using the Cerner Real-World DataTM de-identified COVID-19 cohort
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a proinflammatory condition that can impact the cardiovascular and cerebrovascular systems, thereby increasing risk for thrombotic and thromboembolic events (TTE). However, little is known about the…
Analysis of polygenic selection in purebred and crossbred pig genomes using Generation Proxy Selection Mapping
Background Artificial selection on quantitative traits using selection indices in commercial livestock breeding populations causes changes in allele frequency over time, termed selection signatures, at causal loci and other surrounding genomic regions. Researchers and managers of pig breeding programs are motivated…
Comprehensive Exam: Using subgroup discovery techniques to identify a high-risk group of suicide attempts among people with diabetes
In 2019, 37.3 million Americans had diabetes mellitus, and 1.2 million Americans aged 18 and older had attempted suicide in the past year. According to previous studies, people with type 1 diabetes were three to four times more likely to…
Detecting formation and growth of refugee / displaced person camps in the Ukraine crisis: Assisting first-phase humanitarian response using satellite imagery
Amid the worst population displacement crisis in Europe since World War 2, governments and international organizations have struggled with the massive task of tracking and providing aid to Ukrainian refugees and internally displaced persons (IDPs). This presentation reviews requirements and…
A Computational Respiration Factor to Detect Abnormal Respiratory Patterns Using a Hydraulic Bed Sensor for Older Adults Aging-in-place
Hydraulic bed sensors are efficient non-wearable, passive sensors for unobtrusive and continuous collection of health data for older adults aging-in-place. Continuous collection of data can speak volumes about onset and development of a disease much before it is diagnosed and…
Dissertation Defense: DESIGN AND DEVELOPMENT OF GEOSPATIAL ANALYTICAL RESEARCH KNOWLEDGEBASE (GeoARK)
A consistent finding across health, social, business, and environmental literature is that location matters. To conduct impactful research that can be applied to real-world issues and problems, the research must be grounded within the context of the real world in…