MU-LOC: A Deep Neural Network Method for Predicting Mitochondrially Localized Proteins in Plants
Targeting and translocation of proteins to the appropriate subcellular compartments is crucial for cell organization and function. Newly synthesized proteins are transported to mitochondria with the assistance of complex targeting sequences containing either an N-terminal pre-sequence or a multitude of…
An Analysis of Diabetes Mobile Applications Features Compared to AADE7TM: Addressing Self-Management Behaviors in People with Diabetes
Diabetes Self-management (DSM) applications (apps) have been designed to improve knowledge of diabetes and self-management behaviors. However, few studies have systematically examined if diabetes apps followed the American Association of Diabetes Educators (AADE) Self-Care BehaviorsTM guidelines. The purpose of this…
Collaborations across disciplines: MU Thyroid Nodule Electronic Database (MU-TNED), a multidisciplinary informatics approach
Thyroid nodules are common findings and thyroid cancer is projected to be one of the leading causes of cancer in women. The EHR includes the necessary data needed to connect clinical research with patient outcomes. The objective for this project…
Use of the N-ary Relational Schema to Atomize Compound Relational Triples
Electronic medical records document health information in structured format and in unstructured free text format. Health information in structured format contains laboratory results, vital signs, patient demographics etc. The unstructured free text is the prime source of healthcare information documenting…
Effects of evolutionary pressure on histone modifications
With the advent of next-generation sequencing technologies, a considerable effort has been put into sequencing the epigenomes of different species. The efforts such as “Encode” and “Roadmap” epigenomics projects provide an opportunity to compare epigenomes across species (especially between human…
Investigating genome composition in multiple bee species
The honey bee Apis mellifera was the first eusocial animal to have its genome assembled. Analysis of the complete draft sequence of the honey bee genome revealed several interesting features compared with the other metazoan genomes: a low but heterogeneous…
A Geospatial Health Context Table for Supporting Public Health Research
This project develops a Big Data table that allows researchers to query across and among multiple data sources integrated by location. The big table created in this way uses location as the fundamental linkage between data sets. This is the…
Blockchain Technologies for Healthcare – Technical Challenges and Potential Applications
Blockchain is a technology of distributed ledger originally applied in the financial world. Bitcoin is one of the most adoptable cryptocurrencies based on Blockchain technique. The success of Bitcoin in technology means Blockchain has the potential for decentralized transaction validation, data provenance, data sharing, and…
Data Mining for Genetic Combinations Relevant to Autism Subtypes
Autism is characterized by a complex set of behavioral, social, and cognitive deficits. Extensive variation of these phenotypes suggests the existence of autism subtypes that likely have distinct genetic etiologies. The lack of unifying genotypes common to autism patients supports…