An embarrassingly parallel application: High accuracy mapping of copy number variable regions
Finding gene copy number variation in a species is the cornerstone of genomic research. Most CNV finding tools and methods rely on comparing samples to the reference genome and on detecting certain signatures in the alignment data. These methods are…
Measuring the Speed and Efficacy of Clinical Decision Making through Medication History Visualizations
The rapid advancements in our ability to store, extract, and analyze data in the 20th and 21st century is overwhelming care providers. Large, diverse, complex and/or longitudinal datasets are continuously generated from a variety of instruments, sensors and/or computer-based transactions. …
Identification of the causal mutation for a congenital limb abnormality in Mediterranean river buffalo
Mediterranean river buffalo have recently undergone strong selection for increased quality and quantity of milk for mozzarella cheese production. Strong selection for traits such as milk production are often associated with increased inbreeding, leading to decreased genetic diversity and an…
Promoting Population Health Through mHealth: Can Personal Health Management System Alter Personal Health Behavior?
Abstract: mHealth provides unprecedented medium to collect valuable information on patients, which was otherwise hard to collect and incorporate into management decision making. Several interventions conducted by a leading university school of medicine to measure the health outcome of its…
Operational Taxonomic Units classification: Diving into Phenetics Approach with the 16S Subunit
Operational Taxonomic Units (or OTUs) are useful approximations for taxonomic species in groups where classification is difficult. As such, OTU classifications based on DNA sequences are commonly used in metagenomics studies to describe sample diversity. Since there are no a…
Researching the communication structure of online health communities with social network analysis and computational linguistics, a group informatics approach
Online communities are virtual social structures that promote communication among Internet users on various discussion subjects. Research has found that online communities make communication possible for every person and are highly active with almost every Web user being a member…
Large-scale biomedical image analysis using Big Data Infrastructure
Biomedical imaging informatics involves the analysis, manipulation, and computational calculation of digitally acquired biomedical images to gain knowledge and insights. Informatics technologies are being developed to assist biomedical researchers to identify meaningful objects from raw images, extract content, process information,…
Developing a Decision Support Software for CINV Prevention
The US National Center for Health Statistics estimated that more than 19 million adults in the US have ever been diagnosed with cancer. Chemotherapy is one of the important modality of cancer treatments. Chemotherapy-Induced Nausea and Vomiting (CINV) are the…
Knowledge Discovery System for Research Hypothesis Generation from Serendipitous Findings
From the discovery of penicillin and x-rays to the development of many of today’s chemotherapy agents, serendipitous findings tangential to the researcher’s intended purpose, the “That’s funny…” moments, have greatly impacted the health and well-being of society. As an information…