Tool Development for Analyzing Arrhythmias in Fast Cardiac Magnetic Resonance Scans
Cardiac magnetic resonance (CMR) scanning provides a method to diagnose cardiac disease. For obtaining an effective image, the standard procedure of CMR requires patients to hold their breath during the scanning, but it is difficult for frail patients in clinic.
Early Detection of Glaucoma Using Electronic Health Records
Glaucoma is the second leading cause of irreversible blindness worldwide. About 70 million people have glaucoma, and nearly 4.4 million people are blind from optic nerve damage due to undiagnosed glaucoma. Besides, the current glaucoma growth rate and its economic…
Evaluation of chronic disease self-management information on social media using evidenced-based frameworks
The management of chronic diseases requires considerable patient education and self-management. Diabetes, cancer and mental illness are among the top ten searched chronic diseases on social media, a platform where people increasingly seek and disseminate information. Social media platforms such…
Analysis of snRNA-seq from CDX Models of Non-Small Cell Lung Cancer Identified Subpopulation of Cells Potentially Responsible for Tumor Progression
Circulating tumor cells (CTCs) are considered as seeds of metastasis and have potential to be used as biomarkers in cancer. Understanding the biology of CTCs is critical to evaluate tumor progression and response to treatment. Additionally, studying transcriptome of CTCs–derived tumors…
What to Learn and What to Avoid from ClinicalTrials.gov for New Trial Design When Repurposing Drugs for Precision Medicine?
Clinical trials are essential in the process of new drug development and repositioning. As clinical trials involve significant investments of time and money, it is crucial for trial designers to carefully investigate trial settings prior to launching it. In the…
A Case-Control based Genomic Analysis of Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD) is a respiratory illness that affects millions of people all over the world. It is a major cause of chronic morbidity and mortality and a serious global public health problem. COPD is the fourth leading…
Risk Factors for Thyroid Cancer, a Systematic Review
Thyroid cancer accounted for 1 out of every 20 female cancer diagnoses worldwide in 2018; the etiology of this disease is not well understood, and preventive programs are not established. It is well known that thyroid cancer incidence has been increasing…
FatPlants: A Comprehensive Website Platform of Plant Fat Related Genes, Proteins and Metabolism
Increasing seed oil content by plant breeding has resulted in trade-offs or penalties with respect to protein content, seed size, or seed set. The molecular basis for this impasse is mostly speculative. Use of current global profiling approaches to better…
Development of A Blockchain Framework for Virtual Clinical Trials
Clinical trials are essential for discovering new treatments, but there are multiple challenges to patient recruitment, patient engagement, and cost containment. Virtual clinical trials (VCT) are an innovative approach that provides potential solutions by conducting home-based, rather than site-based, clinical…