The power and challenges of single cell gene expression technology
For many common diseases, a significant percentage of patients simply do not respond effectively or have adverse side-effects to any given treatment. To more successfully focus our disease intervention targets, comparatively diverse species with high-resolution starting points are required. An…
The promise of precision medicine: A focus on genomics and bioinformatics
Chromosomal rearrangements leading to the generation of gene fusions are more common in pediatric malignancies compared to adults and possess diagnostic and prognostic value. Identification of novel gene fusions provides a means for patient stratification and the foundation for the…
Use of Powerful Tools for Meaningful Conclusions from Sparse Data
At any given time, over 10 million women are pregnant or lactating in the United States, about 80% of these pregnancies result in a normal pregnancy and life birth. The remaining are associated with a wide range of pregnancy related…
Big Data Colloquium Distinguished Speaker – Dr. Jianjiong Gao
Thanks to the advancements of technology such as next-generation sequencing, an overwhelming amount of cancer genomics data has been generated by large-scale cancer genomics projects such as The Cancer Genome Atlas (TCGA). This has imposed an increasing challenge in the…