Application of Deep Learning in Predicting Phenotypes

Genomic selection (GS) can use single-nucleotide polymorphism (SNPs) markers to predict breeding values (BV) for enhancing quantitative traits in breeding populations. GS has been proved to increase breeding efficiency in both plant and animal breeding. However, existing statistical and machine-learning…

Promoting Healthy Coping in seniors 72 years or older with Type 2 Diabetes: A feasibility study of a mobile diabetes self-management and support application on functionality, readability, and usability

One out of four Americans older than 65 years old has diabetes.Type 2 diabetes accounts for about 90% to 95% of all diagnosed cases of diabetes. Mobile health technology provides possible solutions for seniors with type 2 diabetes to manage…

Informatics framework for the identification of diagnostic discrepancies and errors

Diagnostic “grey zones” is a term used in pathology, the study of diseases, to describe overlapping morphologic, immunophenotypic and genetic features among various disease subtypes that can lead to diagnostic pitfalls and errors in classifying cancer (e.g. lymphomas). Diagnostic pitfalls…

Contrast mining to discover combinations of genetic factors associated with autism subgroups

Autism is characterized by a complex set of behavioral, social, and cognitive deficits. Extensive variation of these phenotypes suggests the existence of autism subtypes that likely have distinct genetic etiologies. The lack of unifying genotypes common to autism patients supports…

MUII Comprehensive Exam- Saad Khan

Comparison of histone modifications across species A cell’s identity is determined by distinct sets of genes that are expressed at a given point of time. An important factor in determining which set of genes are expressed is the cells epigenome.

MUII Comprehensive Exam – Awatef Ben Ramadan

Steps in Transforming the Missouri Cancer Registry (MCR) from an Incidence Registry to a Survival Registry The Problem: Breast cancer is the most common invasive cancer among women of all races and ethnicities in the United States (US). About 12…

MUII Comprehensive Exam Announcement – Lynsey Whitacre

De novo assembly and comparison of whole genome consensus sequences for nine breeds of beef cattle With the recent rise in re-sequencing efforts fueled by next-generation short read sequencing technologies, we have lost sight of the overarching goal of trying…