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Application of Deep Learning in Predicting Phenotypes

Genomic selection (GS) can use single-nucleotide polymorphism (SNPs) markers to predict breeding values (BV) for enhancing quantitative traits in breeding populations. GS has been proved to increase breeding efficiency in both plant and animal breeding. However, existing statistical and machine-learning methods require imputation to missing values in genotypes, which leads to poor generalization and computation

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Promoting Healthy Coping in seniors 72 years or older with Type 2 Diabetes: A feasibility study of a mobile diabetes self-management and support application on functionality, readability, and usability

One out of four Americans older than 65 years old has diabetes.Type 2 diabetes accounts for about 90% to 95% of all diagnosed cases of diabetes. Mobile health technology provides possible solutions for seniors with type 2 diabetes to manage their daily lives. However, our preliminary research shows that only 10% of diabetes apps provided

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Informatics framework for the identification of diagnostic discrepancies and errors

Diagnostic “grey zones” is a term used in pathology, the study of diseases, to describe overlapping morphologic, immunophenotypic and genetic features among various disease subtypes that can lead to diagnostic pitfalls and errors in classifying cancer (e.g. lymphomas). Diagnostic pitfalls are risks that pathologists should be aware of and avoid, and diagnostic errors are failures

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Contrast mining to discover combinations of genetic factors associated with autism subgroups

Autism is characterized by a complex set of behavioral, social, and cognitive deficits. Extensive variation of these phenotypes suggests the existence of autism subtypes that likely have distinct genetic etiologies. The lack of unifying genotypes common to autism patients supports this subtype structure, and suggests that the onset of autism is due to combinations of

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MUII Comprehensive Exam- Saad Khan

Comparison of histone modifications across species A cell’s identity is determined by distinct sets of genes that are expressed at a given point of time. An important factor in determining which set of genes are expressed is the cells epigenome. Epigenomes are known to play an important role across all eukaryotic species in gene regulation,

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MUII Comprehensive Exam – Awatef Ben Ramadan

Steps in Transforming the Missouri Cancer Registry (MCR) from an Incidence Registry to a Survival Registry The Problem: Breast cancer is the most common invasive cancer among women of all races and ethnicities in the United States (US). About 12 percent of women will be diagnosed with breast cancer in one stage of their lives

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MUII Comprehensive Exam Announcement – Lynsey Whitacre

De novo assembly and comparison of whole genome consensus sequences for nine breeds of beef cattle With the recent rise in re-sequencing efforts fueled by next-generation short read sequencing technologies, we have lost sight of the overarching goal of trying to understand what functions a genetic variant has at the molecular level, which is one

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