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Overhead imagery training data quality control: Methods for deep feature label anomaly detection

Spatial analysis of large remotely-sensed imagery (RSI) training datasets for within-class variation and between-class separability is key to uncovering issues of data diversity and potential bias, not just when vetting datasets for usage, but also during the actual dataset creation stage. Project managers of complex imagery annotation campaigns have a largely unaddressed need for tools that continuously

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Biological pathways as graphs: comparison of select similarity methods

We extracted biomedical pathways from 47 publications related to non-small cell lung cancer (NSCLC) and mergedthem into a Neo4j graph database. With this graph serving as ground truth for comparing to other pathways that were extracted from other publications, we investigated several methods of calculating graph similarity. Unlike ontologies and engineered data sets that have uniform representations of data objects, graphs extracted from unstructured texts haveto be compared as text-described entities first, and by using common graph similarity methods second. In this work, we discuss ways of comparing biological graphs composed of text-described

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Impact of diabetes status and other factors on risk for thrombotic and thromboembolic events: A multicenter, retrospective analysis using the Cerner Real-World DataTM de-identified COVID-19 cohort 

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a proinflammatory condition that can impact the cardiovascular and cerebrovascular systems, thereby increasing risk for thrombotic and thromboembolic events (TTE). However, little is known about the impact of diabetes status on risk for TTEs during SARS-CoV-2 infection. In this US-based, multicenter

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Analysis of polygenic selection in purebred and crossbred pig genomes using Generation Proxy Selection Mapping

Background Artificial selection on quantitative traits using selection indices in commercial livestock breeding populations causes changes in allele frequency over time, termed selection signatures, at causal loci and other surrounding genomic regions.  Researchers and managers of pig breeding programs are motivated to understand the genetic basis of phenotypic diversity across genetic lines, breeds, and populations using

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Detecting formation and growth of refugee / displaced person camps in the Ukraine crisis: Assisting first-phase humanitarian response using satellite imagery

Amid the worst population displacement crisis in Europe since World War 2, governments and international organizations have struggled with the massive task of tracking and providing aid to Ukrainian refugees and internally displaced persons (IDPs). This presentation reviews requirements and explores solutions for AI-assisted monitoring of formation of ad-hoc refugee encampments and temporary/informal settlements in

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A Computational Respiration Factor to Detect Abnormal Respiratory Patterns Using a Hydraulic Bed Sensor for Older Adults Aging-in-place

Hydraulic bed sensors are efficient non-wearable, passive sensors for unobtrusive and continuous collection of health data for older adults aging-in-place. Continuous collection of data can speak volumes about onset and development of a disease much before it is diagnosed and that is our vision through this work. Hydraulic bed sensor data yields signal from which

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Development of AI Models for Remote Sensing City Fitness

Tracking a city’s fitness is particularly important for the continued urbanization of civilization. Urban environmental and air quality and overall fitness are decreasing due to natural and anthropogenic events, causing degradation of living quality and leading to various population health issues, including heart and lung problems and even premature death. City fitness monitoring is mostly

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Tool development for resolving and visualizing irregular heartbeats measured by cardiac magnetic resonance

Atrial fibrillation (AFib) is the most common irregularity of heartbeats. it can cause significant symptoms and impair heart function and daily life. Its irregular and often very rapid heart rhythm can lead to blood clots that cause stroke or heart attack, especially as the patient ages. The irregularity of heartbeats has prevented visualization of the

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Single-cell immune profiling of Q fever vaccination in mice

Human Q fever is a worldwide zoonotic disease caused by intracellular Gram-negative bacterium, Coxiella burnetii. Human Q fever has high infectious nature. However, there is no FDA approved vaccine in the US. Previous studies showed that after serial passages in eggs and tissue cultures, C. burnetiid undergoes a lipopolysaccharide (LPS) phase variation in which its

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Identification of biomarkers and therapeutic combinations for immune checkpoint inhibitors (ICIs) using explanatory subgroup discovery for cancer patients without EGFR mutation

Phenotypic and genotypic heterogeneity are characteristic features of cancer patients. To tackle patients’ heterogeneity, immune checkpoint inhibitors (ICIs) represent one of the most promising therapeutic approaches to treat cancer. However, 50% of cancer patients that are eligible for treatment with ICIs will not respond well to this kind of therapies. Over the years, multiple patient

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