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P3DB-4.0: a large-scale plant protein phosphorylation database from diverse species to phosphosite conservation
Presenter:

Chunhui Xu

Date:

10-21-2021

Time:

4:00PM-4:30PM

Location:

ZOOM

Since the last version (version 3) of the P3DB was published in 2014, we are very encouraged to see that more and more plant scientists have been using our database including reanalysis of our data collections. In this new version (version 4.0), we extensively re-innovated our database to a brand-new platform (https://www.p3db.org) for accommodating much

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Predictive Models for Early Detection of Glaucoma using Electronic Health Records
Presenter:

Murugesan Raju

Date:

10-14-2021

Time:

3:30PM-4:00PM

Location:

Zoom

Glaucoma is the second leading cause of irreversible blindness across the world. Around 70 million people have glaucoma, and 4.4 million people are blind due to undiagnosed glaucoma by optic nerve damage worldwide. Studies suggest that early detection of glaucoma is critically essential for the prevention of irreversible blindness. Effective use of electronic health records

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Analysis of tumor associated macrophages’ heterogeneity in colorectal cancer patients using single-cell RNA-seq data
Presenter:

Iuliia Innokenteva

Date:

10-07-2021

Time:

4:00Pm-4:30PM

Location:

Zoom

Colorectal cancer (CRC) is one of the deadliest malignancies worldwide. Though immune checkpoint inhibition has proven effective for a number of other tumors, it offers benefits in only a small group of CRC. In general, heterogenous cell groups in the tumor microenvironment (TME) are considered as the major barrier for unveiling the causes of low

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EXPLAINABLE ARTIFICIAL INTELLIGENCE FOR PATIENT STRATIFICATION AND DRUG REPOSITIONING
Presenter:

Zainab Al-Taie

Date:

09-30-2021

Time:

5:00PM-6:00PM

Location:

Zoom

Enabling precision medicine requires developing robust patient stratification methods as well as drugs tailored to homogeneous subgroups of patients from a heterogeneous population. Developing de novo drugs is expensive and time consuming with an ultimately low FDA approval rate. These limitations make developing new drugs for a small portion of a disease population unfeasible. Therefore, drug repositioning

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Scientific illustrations as a source of biological pathway information
Presenter:

Misha Kovalenko

Date:

09-30-2021

Time:

4:00PM-4:30PM

Location:

Zoom

The idea of cross-referencing distinct areas of knowledge to glean new insights is not new, but not much work has been done with automatic analysis of different expressions of the same knowledge source, such as a given scientific text and illustrations that accompany it. The NLM grant “Image-guided Biocuration of Disease Pathways From Scientific Literature”

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